Yep.
Maybe it's just because when I was little, I was rushed to the ER by my parents at night. Another time, we also had a fire at our house from a chimney issue, so my mind always goes to that memory too. I couldn't imagine my parents dealing with that while high.
And just a month ago, my aunt-by-marriage's sister actually died in a housefire when she left a pot unattended on the stove (and she was a nurse, highly educated woman, and wasn't high or on anything and still had the accident happen and died). So I don't really want to think what would happen with two high adults with two little kids in a similar scenario.
Again, don't care what people do, but these things have to be considered with two littles in the house.