A major fall out can be an eye opener of your friendship imo. It can go either way.
My primary friendship group consisted of four. One *was* my best friend and who I would say is the "main girl" of this group. Not because she is alpha, but for the fact she is very bubbly and certainly has a motor mouth but she needs constant reassurance and attention. She has BPD so I totally get it but at the same time, the constant need for attention wore really thin when I had a baby last year and if I did not reply to her messages right away she would ask if she had done anything wrong or if I had fallen out with her. I always replied, just not right away. I got frustrated and we ended up yelling at eachother over the phone, she even said I was out of order for not having her as my birth partner in her anger (I had my sister). Next time we all met up, it was so awkward, she started declaring another in the group as her "bestie" as she had grown closer to her. They became so co-depenadant and quite exclusive to each other to the point myself and even outsiders had thought they had become an item. I saw less of my best friend as a result. Anyhow, she eventually fell out with the other girl recently, me and the forth girl in the group knew it was going to happen, it was like watching a car crash (it was very very messy, lots of bitching, accusations) and they now no longer talk at all. The group has kind of dissolved. We no longer all meet up. I see very little of them. My "best friend" I have seen on her own since but she just seems different. It seems awkward, it just isn't the same. It almost feels like I am being used, as a back up plan for someone to depend on. It just doesn't feel like a natural friendship anymore. I don't know if anyone can relate but it is such a shame.
I think it can be quite a depressing and lonely time too.