I am betting they all might have an issue with his drinking. All of his "friends" have content on tiktok or youtube and if you look, you won't see him on there as much. LBV and WDWcouple (two hacks if you ask me) don't put him on their content and they are supposed friends. The only ones I really see him with are the Kingdom Krew. And let me just put it out there, that "krew" is nothing but an immature bunch of trainwrecks so I can see why Nate gets along with them.I think Sam or Jackie herself might've started to find issue with the excessive drinking. Different channel direction could be a part of it too but I don't think that alone would cause them to separate as much as they have now.
Nate's consumption adds up to a lot financially, a lot of calories and a big disruption to anyone working towards a healthier and happier lifestyle. He seems like the type that begs you to join him for drinks as well which doesn't bother me with a little moderation but gets tiring after a bit, and is also dangerous if you're driving afterwards. Just because Nate has a mysterious friend that drives him home from the parks and back to his car in the morning doesn't mean that Jackie and Sam do too.
I also don't think he has anyone to drive him. That was clearly made up when he was called out on his drinking and potential DWI. My guess is that's why he sticks to Disney content and nothing else in Central FL because he lives closer to Disney. This way he has a "lesser chance" of getting pulled over and having to take a breathalyzer test. His channel has become stale and it's now "eat, drink, giggle like a child, repeat". Other content creators looking to grow don't want someone like that dragging them down and potentially creating negative feedback due to his drinking and purple face antics.
Or it could just be that they all shower and wash their faces? Who really knows....