COVID-19 vaccine #22 & general vaccine conversation

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Freedomofspeech89

Freedomofspeech89

monga said:
I don't know my son had the flu vaccine and had no side effets at all ( he chose to have it )

Seems there are outbreaks of scarlet fever
www.mylondon.news

Child at Ealing primary school dies of invasive strep A with another in hospital

Several children are off sick with scarlet fever at a neighbouring school, which can be caused by strep A
www.mylondon.news www.mylondon.news
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My daughter had it when she was 3 and she was extremely ill after. Never let her have it again. Think it affects everybody differently but I don't think they should be giving it to young children.
 
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monga

monga

Freedomofspeech89 said:
My daughter had it when she was 3 and she was extremely ill after. Never let her have it again. Think it affects everybody differently but I don't think they should be giving it to young children.
Click to expand...
My sons always had it ,once he had a rash under his nose but no other symptoms.
 
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D

dinosaursideways

Freedomofspeech89 said:
This may be a ignorant question. But how do they diagnose and differentiate between all of these viral infections?
Click to expand...
You quoted something about Group A Strep which isn't a virus, it's a bacterium.

Viruses can be swabbed for, but diagnoses can be made based on the clinical presentation and context - symptoms, known contacts, community prevalence, testing, other diagnostics, disease progression, clinical suspicion. E.g. if someone lives in a household with people who have covid symptoms, some of whom have tested positive, and that person has the same symptoms - even if they don't test or test negative, we would still suspect them of having covid. Could be something else but the likelihood is covid. E.g. on xray covid lungs look very different to flu/pneumonia lungs. Different diseases also respond differently to different treatments and can progress differently, which can also be an indicator. For example, initial syphilis and herpes infections can be pretty similar (flu-like illness, 1+ small lesions) but primary syphilis progresses to secondary syphilis, whereas herpes may become dormant or cause repeated outbreaks. At that stage they are much more distinguishable from each other. I think people often fail to understand that healthcare especially initially is to an extent best-guess guesswork that takes into accounts risks, benefits, and likelihoods.

People can also have multiple infections at once - including both viral and bacterial infections at the same time, or multiple viral infections. You could have flu and then develop a secondary bacterial chest infection with it, or be co-infected with flu and covid. Diagnosis and treatment decisions aren't always and solely dependant on test results, but can be informed by the whole clinical picture. And it's good they are not because tests especially microbiology diagnostics take time and you can't necessarily wait to treat.

Re GAS, because I think it's worth highlighting. You can carry GAS in the throat and on the skin without necessarily developing any of the numerous bacterial infections and post-infection complications it causes (strep throat/tonsillitis, impetigo, scarlet fever, rheumatic fever as a later complication if the scarlet fever isn't treated, and also the invasive infections (IGAS) that includes necrotizing fasciitis, streptococcal toxic shock syndrome). It can cause mild infections and very nasty, deadly infections. GAS can be cultured from swabs for e.g. if it's in the throat, but for scarlet fever doctors would normally go off the clinical picture to diagnose. If someone has an iGAS infection they will be unwell enough to be in hospital and blood cultures would be done but again, they wouldn't wait for the results back they would start treatment based on the clinical picture.

You cannot develop immunity to GAS and you cannot build up immunity to GAS by being exposed to GAS or other pathogens.
 
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monga

monga

dinosaursideways said:
You quoted something about Group A Strep which isn't a virus, it's a bacterium.

Viruses can be swabbed for, but diagnoses can be made based on the clinical presentation and context - symptoms, known contacts, community prevalence, testing, other diagnostics, disease progression, clinical suspicion. E.g. if someone lives in a household with people who have covid symptoms, some of whom have tested positive, and that person has the same symptoms - even if they don't test or test negative, we would still suspect them of having covid. Could be something else but the likelihood is covid. E.g. on xray covid lungs look very different to flu/pneumonia lungs. Different diseases also respond differently to different treatments and can progress differently, which can also be an indicator. For example, initial syphilis and herpes infections can be pretty similar (flu-like illness, 1+ small lesions) but primary syphilis progresses to secondary syphilis, whereas herpes may become dormant or cause repeated outbreaks. At that stage they are much more distinguishable from each other. I think people often fail to understand that healthcare especially initially is to an extent best-guess guesswork that takes into accounts risks, benefits, and likelihoods.

People can also have multiple infections at once - including both viral and bacterial infections at the same time, or multiple viral infections. You could have flu and then develop a secondary bacterial chest infection with it, or be co-infected with flu and covid. Diagnosis and treatment decisions aren't always and solely dependant on test results, but can be informed by the whole clinical picture. And it's good they are not because tests especially microbiology diagnostics take time and you can't necessarily wait to treat.

Re GAS, because I think it's worth highlighting. You can carry GAS in the throat and on the skin without necessarily developing any of the numerous bacterial infections and post-infection complications it causes (strep throat/tonsillitis, impetigo, scarlet fever, rheumatic fever as a later complication if the scarlet fever isn't treated, and also the invasive infections (IGAS) that includes necrotizing fasciitis, streptococcal toxic shock syndrome). It can cause mild infections and very nasty, deadly infections. GAS can be cultured from swabs for e.g. if it's in the throat, but for scarlet fever doctors would normally go off the clinical picture to diagnose. If someone has an iGAS infection they will be unwell enough to be in hospital and blood cultures would be done but again, they wouldn't wait for the results back they would start treatment based on the clinical picture.

You cannot develop immunity to GAS and you cannot build up immunity to GAS by being exposed to GAS or other pathogens.
Click to expand...
Not always as regards Scarlet Fever, it's not very easy to disgnose by sight /symptoms alone ,they usually swab to make sure before contacting public health.

*diagnose
 
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rainbowlemon

rainbowlemon

For anyone expecting something saucier from his title 🤪

This is what he's talking about:

1670184087259.png
 
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A

Anelecin

I came across this on Twitter- apparently by someone who works in the pharmaceutical industry.

As you scroll down, there are lots of offshoot threads on several topics. Some may be of interest?

 
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rainbowlemon

rainbowlemon

Strep A vax in development:

www.ualberta.ca

Researchers launch clinical trial for strep A vaccine

An international team of researchers is launching the first phase of human clinical trials for a vaccine against streptococcus A bacteria, which kills more than 500,000 people a year worldwide.
www.ualberta.ca www.ualberta.ca

Also those crazy conspiracy theorists claiming some vaccines do shed.

pubmed.ncbi.nlm.nih.gov

Shedding and immunogenicity of live attenuated influenza vaccine virus in subjects 5-49 years of age - PubMed

This is the first study to comprehensively evaluate nasal shedding of LAIV in individuals 5-49 years of age. Shedding was generally of short duration and at low titers. Study findings support the current recommendation of the Advisory Committee on Immunization Practices that LAIV recipients...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
 
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Freedomofspeech89

Freedomofspeech89

rainbowlemon said:
Strep A vax in development:

www.ualberta.ca

Researchers launch clinical trial for strep A vaccine

An international team of researchers is launching the first phase of human clinical trials for a vaccine against streptococcus A bacteria, which kills more than 500,000 people a year worldwide.
www.ualberta.ca www.ualberta.ca

Those crazy conspiracy theorists claiming some vaccines do shed.

pubmed.ncbi.nlm.nih.gov

Shedding and immunogenicity of live attenuated influenza vaccine virus in subjects 5-49 years of age - PubMed

This is the first study to comprehensively evaluate nasal shedding of LAIV in individuals 5-49 years of age. Shedding was generally of short duration and at low titers. Study findings support the current recommendation of the Advisory Committee on Immunization Practices that LAIV recipients...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
Click to expand...
What, the illness the media keep talking about is the same illness they're creating a vaccine for!!?

 
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rainbowlemon

rainbowlemon

Joint research in different countries.

Wonder if they did find out what was causing the hepatitis in kids.
 
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