Yes my ibs is definitely a lot worse when I’m anxious or stressed. Maybe it’s worth him switching to something like metazapine? I was on it for anxiety but you take it at night as it also helps with sleep. It’d knock me out and I’d sleep about 10 hours I felt great the next day. It might be better if he’s on one tablet rather than both?Thanks. I called on Monday asking just for a call back as I didn't want to drag him to the surgery but they said he had to come in. The doctor we saw was more sympathetic and did ask if he wanted to try something else. As he'd not been on them long we thought maybe he should persevere a bit. He slept a bit Monday night with the sleeping pill and didn't feel too bad yesterday morning, although a bit groggy, but then his anxiety just ramped up as the day went on. It seems to stem from if his stomach is a bit off. There's a lot to be said for the brain gut connection I think. Especially when like him he has ibs & ibd. By the time it came to bedtime he was getting anxious about being able to sleep I think.