I hope Brian doesn't have a recurrence after his nephrectomy. Life with just one kidney will mean he needs to look after it.
Sadly I see so many younger people with RCC have a recurrence a few years down the line. RCC is very sneaky type of cancer.
I'm not excited about the fact that he may be stage 1. His prognosis will depend on if there's been microvascular invasion, if the tumour can be removed with clear margins, where about the tumour is sitting (which pole), how close the tumour is to the renal vein. The biopsy states clear cell RCC , but the tumour itself may contain papillary cells as well as clear cell.
My husband was grade 3 too.
It's a sneaky cancer. Why is RCC sneaky? There's no markers for this cancer, it doesn't show in blood tests. Many patients don't show any symptoms at all. RCC is resistant to chemotherapy and radiotherapy. Treatment is immunotherapy or tyrosine kinase inhibitors (tablets taken daily but the cancer becomes resistant to tki's quickly). It often takes years for metastatic spread to show up on scans because it's a slow growing cancer with slow dividing cells.
Many patients (even stage 1, grade 1's) can be living their life after nephrectomy feeling they have been cured, and bam 4 - 5 years down the line a lung nodule or bone met appears, despite them having clear margins.
I hope Brian's oncologist will look into mutations. Personally, I think doing a biopsy was too much of a risk. Biopsies carry risks of seeding. Oncologists say that there's only a slim risk of seeding @ 1%, but someone is that 1%. If the tumour/mass had to come out anyway, it would have been sent to the pathology lab.