My freezer and cupboards are already full, it's still a bit touch and go as to if it will escalate. The Dow has had it's biggest fall ever.
Paste from reddit, the combination of the infection rate, doubling rate and mortality rate are concerning.
Basics:
- Name of virus: SARS-CoV-2
- Name of illness: COVID-19
- R0 SARS-CoV-2: 2.28 - 3.28 2,27
- R0 Seasonal Influenza: 1.28 19
- COVID-19 Case Fatality Rate: 2.3% - 4.3% 3, 4 (Note that CFR is very difficult to estimate accurately in any situation, but especially in an evolving situation like this)
- 2019-2020 Influenza Fatality Rate: 0.039% - 0.14% 5
- Confirmed Cases (World): 82,738 (2/27/20 1700 EST) 13
- Confirmed Cases (Non-China): 4,265 (2/27/20 1700 EST) 14
- Confirmed Cases (US): 60 (2/27/20 1700 EST) 15
- Case Doubling Time (Non-China): 6 days 18
- Transmission Methods: Respiratory droplet and touch/fomites 6, possible fecal-oral 21, possible airborne 28,29
- Incubation Period: 2-14 days 7
- Persistence on Inanimate Surfaces: Up to 9 days. Less at temperatures above 30C 27
Symptoms: Fever, cough, SOB
8.
It seems to start with a fever, followed by a dry cough. After a week, it can lead to shortness of breath, with about
20% of patients requiring hospital treatment. Notably, the COVID-19 infection rarely seems to cause a runny nose, sneezing, or sore throat
9. Some atypical patients
may present initially with GI symptoms.
Clinical Features: Pneumonia appears to be the most frequent serious manifestation of infection, characterized primarily by fever, cough, dyspnea, and bilateral infiltrates on chest imaging. Most infections are not severe, although many patients have had critical illness. In a report from the Chinese Center for Disease Control and Prevention that included approximately 44,500 confirmed infections with an estimation of disease severity, 81 percent were mild (no or mild pneumonia), 14 percent were severe (eg, with dyspnea, hypoxia, or >50 percent lung involvement on imaging within 24 to 48 hours), and 5 percent were critical (eg, with respiratory failure, shock, or multiorgan dysfunction). White count is variable. In a study involving PNA pts, "
lymphopenia was common, and all patients had parenchymal lung abnormalities on computed tomography of the chest, including bilateral patchy shadows or ground-glass opacities." Acute respiratory distress syndrome developed in 20 percent, and mechanical ventilation was implemented in 12.3 percent. Among the six patients who died, D-dimer levels were higher and lymphopenia was more severe compared with survivors.
23
Treatment:
Treatment is primarily supportive. The following medications have either been tentatively shown to be efficacious, or are under investigation as treatment