I think as reasonable humans we understand that interference in nature is a balance of risks, all medicine is a balance of risk of treatment against risk of no treatment. Surgery is a risk, usually it is less than not having it. Cosmetic surgery is a risk, but the reward is considered worth it and sometimes - like Kanye’s mum, people die after liposuction. Cancer drugs also cause horrible side effects to the point sometimes people choose quality of life. Puberty blockers have always had horrific side effects, they are used for precocious puberty when weighed up against the effect of letting very small children go through puberty. Everyone knows they cause harm as part of the treatment. so the gotcha of ‘they are safe to use as we use them for ‘cis’ kids’ is bollocks.
Using Lupron to treat a mental illness is deranged. These kids are losing IQ points, their brains will not fully develop. The BMA council are overturning the basis of their profession, the Hippocratic oath, doctors should be horrified.